The use of long-acting somatostatin analogs in congenital hyperinsulinism
نویسندگان
چکیده
منابع مشابه
Successful treatment of congenital hyperinsulinism with long-acting release octreotide.
CONTEXT Congenital hyperinsulinism (HI) is a common cause of hypoglycemia in infancy. The medical treatment of diazoxide-unresponsive HI is based on a somatostatin analogue. OBJECTIVE This study aims at replacing three daily s.c. octreotide (Sandostatin, Novartis) injections by a single and monthly i.m. injection of long-acting release (LAR) octreotide (Sandostatin LP, Novartis) in HI patient...
متن کاملA New Experience in Treatment of Congenital Hyperinsulinism with Long Acting Octreotide: A Case Report
Histologically, congenital hyperinsulinism may be broadly classified into focal and diffuse forms. Although they present with similar clinical manifestations, they differ in the management required. Focal forms of CHI, unlike the diffuse forms are amenable to surgery without any long term sequlae [4]. Owing to the fact that, near-total pancreactectomy often leads to postoperative hypoglycemias ...
متن کاملLong-Acting Human Insulin Analogs
Endogenous insulin is a hormone secreted by the beta cells of the pancreatic islets of Langerhans. Insulin acts via specific membrane-bound receptors on target tissues to regulate metabolism of carbohydrates, proteins and fats. Exogenous insulin, manufactured for pharmacologic use through recombinant DNA technology using either E. coli or Saccharomyces cerevisiae is used as replacement therapy ...
متن کاملPrescription patterns of long-acting somatostatin analogues
BACKGROUND Acromegaly and endocrine tumors are uncommon morbidities that are currently treated with different drugs. OBJECTIVE To determine the prescription patterns of somatostatin analogues in patients affiliated with the Health System of Colombia. METHODS Retrospective cohort study of patients of any age and sex treated with octreotide or lanreotide between January 2011 and August 2015. ...
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Gastric endocrine tumors associated with autoimmune chronic atrophic gastritis (gastric carcinoid type I) are almost exclusively benign lesions with little risk of deep invasion of the gastric parietal wall. For this reason, the role of octreotide in the treatment of these neoplastic lesions is controversial. Nine patients with more than five type I gastric endocrine tumors each <1 cm in size, ...
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ژورنال
عنوان ژورنال: Problems of Endocrinology
سال: 2020
ISSN: 2308-1430,0375-9660
DOI: 10.14341/probl12654